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It functions as a unimolecular dual agonist with high affinity for both the Glucose-Dependent Insulinotropic Polypeptide (GIP) receptor and the Glucagon-Like Peptide-1 (GLP-1) receptor

However, 2025 research looking at databases from the United States, Canada, and Australia found that people taking tirzepatide were significantly more likely to report insomnia than people taking other medications

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This positions #oral #GLP-1 #therapies as a credible long-term alternative to injectables, potentially expanding the #addressable market by improving patient #convenience, #adherence, and #scalability

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